Abstract
Even though in italy definite rules of driving under influence of illegal substances, drugs and alcohol, have to be approved under the traffic code, a fast screening procedure is described that allows the identification of the presence, in blood and urine, of the most common substances that normally influence the driving ability. This procedure is based on separation from the blood and urine of acid, neutral and basic substances using solid phase extraction, with bon elut certify cartridges. A single determination with various type of solvents and at different ph is carried out for each sample. The extracts are then analyzed by linear programmed gc/ms, using capillary column. (A)