Determination of pholcodine together with other opiates in urine and blood samples by gas chromatography/mass spectrometry (GC/MS).

Author(s)
Mykkanen, S. Ariniemi, K. Nummi, P. & Lillsunde, P.
Year
Abstract

A GC-MS (gas chromatography-mass spectrometry) method for simultaneous determination of pholcodine, morphine, codeine, 6-acetylmorphine, dihydrocodeine and ethylmorphine in urine and blood is described. The method employs propionic anhydride in the presence of triethylamine to propionylate free hydroxyl groups of the opiates. Confirmation is achieved using gas chromatography/mass spectrometry in the electron impact mode.

Request publication

7 + 3 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.

Publication

Library number
C 17214 (In: C 17017 [electronic version only]) /83 / ITRD E107523
Source

In: Alcohol, drugs and traffic safety T2000 : proceedings of the 15th ICADTS International Conference on Alcohol, Drugs and Traffic Safety, Stockholm, Sweden, May 22nd - 26th, 2000, pp.-

Our collection

This publication is one of our other publications, and part of our extensive collection of road safety literature, that also includes the SWOV publications.