Effects of fexofenadine, diphenhydramine, and alcohol on driver performance : a randomized, placebo-controlled trial in the Iowa driving simulator.

Author(s)
Weiler, J.M. Bloomfield, J.R. Woodworth, G.G. Grant, A.R. Layton, T.A. Brown, T.L. McKenzie, D.R. Baker, T.W. & Watson, G.S.
Year
Abstract

Previous studies suggest that sedating antihistamines may impair driving performance as much as alcohol does. The participants in this study had similar simulated driving performance when treated with fexofenadine (a nonsedating drug) or placebo. After alcohol use, participants performed the primary task (matching the varying speed of a vehicle they were following) well but not secondary tasks. After participants received diphenhydramine (a sedating drug), driving performance was poorest, indicating that this drug had a greater effect on driving than alcohol did. (A)

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Publication

Library number
20001592 ST [electronic version only]
Source

Annals of Internal Medicine, Vol. 132 (2000), No. 5 (March 7), p. 354-363, 33 ref.

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This publication is one of our other publications, and part of our extensive collection of road safety literature, that also includes the SWOV publications.