Inducing Mild Traumatic Brain Injury in the Rodent through Coronal Plane Angular Acceleration.

Author(s)
Fijalkowski, R.J. Stemper, B.D. Ellington, B.M. Yoganandan, Y. Pintar, F.A. & Gennerelli, T.A.
Year
Abstract

This investigation used a new experimental model to apply pure coronal plane angular acceleration to a rodent, inducing concussion (mild traumatic brain injury). A mass was propelled down a drop tube toward the laterally extended moment arm of a rodent helmet fixture. Upon impact, the rodent helmet-head complex experienced mean angular acceleration of 368 krad/s2 (standard deviation = 30). All 26 specimens demonstrated a period of transient unconsciousness, mild ventriculomegaly, and absence of severe pathology.Injuries were classified as concussion based on scaled biomechanics, transient unconsciousness, macroscopic damage and minimal histological abnormalities. For the covering abstract see ITRD E141569.

Request publication

2 + 4 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.

Publication

Library number
C 46187 (In: C 46159 CD-ROM) /84 / ITRD E141578
Source

In: Proceedings of the 2006 International IRCOBI Conference on the Biomechanics of Impact, Madrid (Spain), September 20-22, 2006, Pp.

Our collection

This publication is one of our other publications, and part of our extensive collection of road safety literature, that also includes the SWOV publications.