Influence of angular acceleration duration on functional outcomes following mild diffuse brain injury.

Author(s)
Fijalkowski, R.J. Stamper, B.D. Pintar, F.A. Yoganandan, N. & Gennarelli, T.A.
Year
Abstract

Diffuse brain injury (DBI) manifests as a spectrum of injuries and severity has been associated with several kinematic based metrics. However, influence of angular acceleration duration is often overlooked. This study provides a focused analysis of angular acceleration duration as a nonexclusive indicator of DBI severity. Functional deficits in rats, measured as timeto reappearance of corneal and righting reflexes, were assessed followingrotationally induced mild DBI. Subjects were exposed to mean angular acceleration durations of 2.0 ± 0.2 msec (mean ± standard deviation), and 3.0 ± 0.1 msec in short and long duration groups respectively. All other rotational kinematics were held constant. Functional deficits increased significantly (p<0.05) as a function of angular acceleration duration. Angular velocity was not sensitive to these functional deficits. Understanding the influence of duration independent of other influencing factors may highlight its role in the DBI mechanism and help identify appropriate DBI metrics.For the covering abstract see ITRD E141762.

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Publication

Library number
C 45981 (In: C 45971 CD-ROM) /84 / ITRD E141774
Source

In: Proceedings of the 2007 International IRCOBI Conference on the Biomechanics of Impact, Maastricht (The Netherlands), September 19-21, 2007, Pp

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This publication is one of our other publications, and part of our extensive collection of road safety literature, that also includes the SWOV publications.