Findings of experimental studies on drugs and driver fitness are of importance for decisions in the fields of traffic safety. Therefore there is an indispensable requirement to do research by an adequate and optimal methodology to produce reliable results. Bearing this fact in mind two international workshops on methodology were organized in Padova and Cologne in 1991 and 1992, cosponsored by ICADTS. Due to the relevance and scope of endeavor needed the ICADTS established a Working Group on this topic in autumn 1994. The goal of this Working Group is to prepare a sound guide to an optimal methodology of experimental studies on drugs and driver fitness, publish these guidelines and attempt to get attempt to get to acceptance by experts, institutions and authorities. Basis of these guidelines should be on the one hand the established national and international guidelines relating to clinical, therapeutic experiments (for example GCP, FDA) that can be adopted for research on drugs and driver fitness and on the other hand the results of the above mentioned workshops including their complementing publications. (A)
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