A model of the intracellular calcium distribution throughout the brain as a function of inertial loading in various planes.

Author(s)
Thibault, L.E. Meaney, D.F. & Gennarelli, T.A.
Year
Abstract

This paper is intended to bring together the results of animal studies, physical model experiments, and isolated tissue investigations. The paper combines the measured strain induced changes for in vitro neural components with the topographic estimates of strain occurring during an inertial loading. The aim is to present a model for intracellular calcium changes throughout the brain immediately post impact. These maps of the calcium events are compared to pathology obtained from subhuman primate studies conducted under similar loading conditions. This approach is intended to provide insight into the relationships between the macroscopic loading parameters and the associated tissue injury.

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Publication

Library number
C 3382 (In: C 3357) /84 / IRRD 871406
Source

In: Proceedings of the 1992 International IRCOBI Conference on the Biomechanics of Impacts, Verona, Italy, September 9-10-11, 1992, p. 311-319, 11 ref.

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This publication is one of our other publications, and part of our extensive collection of road safety literature, that also includes the SWOV publications.