A rapid instrumented fluorescence immunoassay for the detection and quantification of tetrahydrocannabinols (THC) in oral fluids has been developed for use in testing for marijuana abuse. The lower detection limits for (l)-delta9-THC and (l)9-Carboxy-11-nor-delta9-THC was found to be 1.5 ng/mL and 5.5 ng/mL, respectively. Having a total assay reaction time of less than 10 minutes, the assay is ideally suited for use in point-of-care testing of saliva THC by law enforcement and in the workplace.
Abstract