Abstract
The heart was studied in 30 persons who died suddenly from natural causes in the driver's seat of an automobile, truck or bus. Twenty had cardiac arrest while driving and the other 10 while sitting in the driver's seat of a parked vehicle. Victims dying suddenly from coronary artery disease (CAD) while driving are similar to other out-of-hospital sudden coronary death victims with respect to mean age, gender, heart weight, frequency of healed myocardial infarcts, number of major epicardial coronary arteries severely narrowed and the percentage of 5-mm-long segments of the major arteries severely narrowed by atherosclerotic plaque. Most drivers stopped the vehicle without injury to themselves or to others.