Driving under the influence of drugs or impairing medicines reduces fitness to drive[i] and increases crash risk. Drugs have a numbing, stimulating or mind-altering effect on the brain, or a combination of these effects, which impair traffic task performance.

In the Netherlands, a sustainable road safety approach, in which measures in the fields of Engineering, Education and Enforcement (3Es) are complementary, has been used for decades. Enforcement reduces high-risk road user behaviour and is therefore an important component of this safe system approach.

Driver fatigue is estimated to be a (contributing) factor in 15 to 20% of crashes, but estimates in individual studies vary widely. Drivers who are tired are less attentive and react less quickly and less adequately than drivers who are not tired. They also get irritated and frustrated more easily.

A bicycle helmet is intended to protect cyclists against head and brain injuries when they are involved in crashes. The helmet does not prevent bicycle crashes (see the SWOV fact sheet Cyclists for general bicycle safety measures).

In the past ten years (2006-2015) an average of 11 road deaths per year in the Netherlands was registered in crashes involving agricultural vehicles. Compared to the early 1990s, the average number of road deaths due to crashes involving an agricultural vehicle increased from 1% to 2% of the total number of road deaths in the Netherlands.