Accurate estimation of ethanol clearance rate is often necessary in order to calculate a blood alcohol concentration (BAC) at the time of an accident or arrest. To increase the precision of such estimates, the effects of gender, drinking practice and age on ethanol clearance were examined in a between-subjects factorial experiment. Subjects were dosed with alcohol for peak BACs of 85mg/dL or 105 mg/dL. They were breath tested frequently until their peak BAC, and then at hour intervals on the descending BAC curve. Using the post-peak BACs (three or more) an ethanol clearance rate for each subject was calculated with a linear regression analysis. Gender, drinking practice, and age were found to have statistically significant effects on ethanol clearance rates. (A)
Samenvatting