This study presents data from an experimental model of traumatic brain injury coupled with finite element (FE) analyses to evaluate the modeling approach's ability to predict specific forms of traumatic brain injury. Axial plane rotational accelerations produced prolonged traumatic coma in the miniature pig, axonal injury throughout regions of the white matter, and macroscopic hemorrhagic cortical contusions. Results from two-dimensional FE analyses of the miniature pig showed that the manner in which the modeling approach accounts for the relative motions that occurs between the skull and cerebral cortex can dramatically influence the outcome of an analysis. Specifically, this study which compared the numerical response of two different finite element modeling (FEM) approaches with animal injury data from four animal experiments, clearly demonstrated the following: the modeling approach which represented the relative motion between the skull and cerebral cortex as a frictional interface best predicted the resulting injury pattern in a fifth axial plane animal experiment. (A)
Samenvatting