Serum-gammaglutamyl-transferase (gamma-GT, GT, GGT, GGTP) is an enzyme which has been much used in the field of alcoholism during the last decades. Although first introduced as a liver test it had been tested as a market for alcoholism and for heavy drinking, as a screening instrument and as a tool during long-term follow-up of drinkers. It has also been investigated in general populations and correlated with other risk factors besides alcohol consumption, and been described as a predictor of ill health in its own right. GT has been extensively used and compared with other markers of alcohol consumption. It is a cheap and easily used instrument. It can also be studied in the area of traffic safety in the drinking and driving populations and in the rehabilitation of drunken drivers. (A)
Samenvatting