The influence of MDMA on cognition and psychomotor function, and the importance for driving capacity.

In this study the influence of single doses of methylenedioxymethamphetamine (MDMA) 75 mg and alcohol 0.5 g/kg on cognitive and psychomotor performance was assessed in 12 healthy recreational MDMA users. A single recreational dose of MDMA improved tracking performance under single and double task conditions. Movement speed in the choice RT paradigm improved increased after MDMA, while the ability to estimate time to collision was impaired after MDMA. Alcohol impaired tracking performance 1 and 2 hrs after alcohol but returned to baseline levels 3 and 5 hrs after drinking. While MDMA produced both stimulating and impairing effects on skills related to driving, it is concluded that further research employing real driving paradigms and interaction studies with alcohol and possibly THC are (Author/publisher) For the covering abstract of the conference see ITRD Abstract No. E201067.