In essence two different scientific approaches exist to evaluate the effects of psychoactive substances on driving behaviour: epidemiology and experimental studies. The subtask “Meta-Analysis” of Task 1.1 of DRUID (Driving under the influence of Drugs, Alcohol and Medicines) defines the target to evaluate the relevant literature on experimental studies on the effects of psychoactive substances on human performance and driving behaviour for their impact on traffic safety. The evaluation should include - “Medicines regarding to the frequency of driving under medicine influence or the insufficiency of documentation - Drugs regarding to the frequency of driving under drug influence or their novelty with a suspected hazard to driving - Prominent combination of drugs, medicines and alcohol - Alcohol research data will serve as a reference data base” (Description of work). The report at hand picks medicines, drugs (amphetamine, cocaine, cannabis) and prominent combinations out as a central theme whereas the remaining aspects (alcohol, other illegal drugs) will be presented in other deliverables. For medicines and illegal drugs for that exist sufficient relevant literature about their effects on human performance, a meta-analysis is conducted to quantify the results of the experimental studies. (Author/publisher) This document is available at https://www.bast.de/Druid/EN/Home/home_node.html
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