DRUID work package 4 focusses on the classification and labeling of medicinal drugs according to their influence on driving performance. The final goal of this work package is to propose a new classification/categorisation system for the relevant therapeutic groups of medicines available on the European market. The first task (DRUID task 4.1) to reach this goal was making a review of the existing systems. Deliverable 1 of the ROSITA project described the existing systems in 1999.1 An update was necessary because since then new lists have been introduced and some older lists have been updated. In this report, the past and current systems across Europe are described and compared. This document will serve as input for DRUID tasks 4.2 and 4.3 (the establishment of a framework and criteria for a European classification). Therefore it is important that this report allows an easy comparison of the existing systems on two levels: comparison of ratings/labels per molecule; comparison of ratings/labels within one therapeutic class. To achieve this goal, two overview tables were made that include the ratings from the different available systems. In the first overview table (Annex I), the substances are arranged according to the Anatomical Therapeutic Chemical (ATC) classification system. This system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics. Small adaptations were made to the ATC system to further increase readability. In the second overview table (Annex II), the substances are arranged in alphabetic order. Based on these tables, substances and groups of substances were identified for which there is a general agreement or a significant disagreement among the existing classification systems. This list will be serve as input during the first steps of the establishment of new system. (Author/publisher) This document is available at https://www.bast.de/Druid/EN/Home/home_node.html
Samenvatting