A group of 38 volunteers participated in 74 experiments with multiple collection of blood and saliva samples and simultaneous breath testing. BAC/BrAC, BAC/SAC and SAC/BrAC ratios were calculated for every sampling time for each examined person in each experiment. It gave 975 values of the distribution ratio of ethanol for each system. The mean values of BAC/BrAC ratio calculated for absorption and elimination phases differed significantly (1822.1+/-315.9 and 2330.9+/-384.7, respectively, t=19.0, p<0.001). BAC/BrAC ratio slightly grows with increase of ethanol concentration in absorption phase (BAC/BrAC = 1583+/-60 + 466+/-110 x BAC, r=0.26, p<0.001) and with fall of ethanol concentration during elimination (BAC/BrAC = 2758+/-40 - 836+/-75 x BAC, r=-0.39, p<0.001). The difference in BAC/SAC ratio in both phases was also statistically significant (832+/-0.152 and 1.037+/-0.157, t=18.1, p<0.001). SAC/BrAC ratio did not show any dependency on the phase (2217.6 +/- 384.6 and 2264.3 +/- 357.4, t=1.81, p>0.05). Both in the absorption and elimination phase the SAC/BrAC ratio value felt with alcohol concentration (absorption: SAC/BrAC = 2572+/-66 - 595+/-104 x BrAC, r=-0.34, p<0.001; elimination SAC/BrAC = 2514 +/- 33 - 517+/-64 x BrAC, r=-0.29, p<0.001). (Author/publisher) For the covering abstract of the conference see ITRD Abstract No. E201067.
Samenvatting